Home

Red Blood Cell Lab
Meet our Staff
News
Licensing
FAQ

Laboratory Services
Routine Hemoglobinopathy
Molecular Assays
Special Hemoglobin Tests
Red Cell Function Tests
Blood Analysis

Advia 120 analysis
Amino Acid composition
NO metabolism
Hemostasis
Cytokines & Growth factors
Adhesion
Inflammation

Data Evaluation

Resource
Study Facilitation
Database Development
Storage
Assay Development

Hemoglobinopathies
Sickle Cell Disease
Thalassemia
Other Hemoglobinopathies

Red Cells
Red Cell Membranes
Red Cell Lipids
Red Cell Metabolism

Financial Policies
Contact us

 

Human Tissue Factor (TF) ELISA

TF is a membrane-bound glycoprotein predominantly found in lung, brain, placenta, and some tumors. It serves as both the receptor and essential cofactor for factors VII and VIIa in initiating cell surface procoagulant activity, leading ultimately to thrombin generation and fibrin formation. TF thus has a critical role in hemostasis and thrombogenesis.

The TF ELISA is an enzyme-linked immunoassay allowing for the quantitative determination of human TF concentration in fresh or frozen cell lysates, citrated plasma, tumor tissue extracts, or cell culture supernatants. This ELISA recognizes TF-apo, TF, and TF-VII complexes and there is no interference from other coagulation factors or inhibitors of procoagulant activity. This ELISA is for research use only and is not for diagnostic or therapeutic uses.

The standard curve spans the range of 50-1000 pg/ml and the minimum detectable level is 10 pg/mL. The normal range of TF concentration in human plasma remains to be established. Low levels of circulating TF are expected in both normal plasma and in most diseased samples.

Click here for sample collection and shipping.