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 Human Thrombin-Antithrombin Complex III (TAT) ELISA

The measurement of thrombin-antithrombin complexes (TAT) has clinically significant value in the diagnosis of thrombotic events. Elevated concentrations of TAT  are found in persons predisposed to thrombosis as well as in patients with the following: multiple trauma, liver dysfunction, septicaemia, and preeclampsia. In patients with malignant diseases, their levels of TAT increase in relation to the stage of the disease.

The TAT assay is an enzyme immunoassay for the quantitative determination of thrombin/antithrombin III complex (TAT) in human plasma and is used for the diagnosis of disturbances in blood coagulation, which are associated with changes of the activity of the coagulation system. The TAT ELISA is for research use only, not for diagnostic or therapeutic procedures. The standard curve spans the range of 20-600 pM. Normal plasma levels of TAT are less than 3.0 µg/L.

 

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