Exhaled Nitric Oxide (NO)
Nitric Oxide is an important messenger molecule involved in many physiological and pathological processes within the mammalian body. Appropriate levels of NO production are important in protecting an organ such as the liver from ischemic damage. NO can be measured in the exhaled breath or from liquid samples such as blood and urine.
Nitric Oxide is collected from exhaled breath at 350 mL/s (ATS recommendation) into reusable mylar bags in which samples are stable for 8-12 hours after collection. The breath analysis is performed remotely with the Sievers Nitric Oxide Analyzer (NOA). This instrument is highly sensitive (<1ppb) and responds quickly (200ms). Data collection is performed with PC or MAC software with statistical results output and an export facility for further analysis.